Over the last few decades, many Greek professionals have emigrated to look for professional, academic, and research-related employment. Today and as a result of the decade-long 2008 economic crisis, the number of professionals that work abroad is estimated to be more than 250,000 professionals.1 Now, with the first signs of economic recovery in Greece, connecting with those individuals and offering pathways through which this highly educated human capital can collaborate with the domestic academic, research, and entrepreneurial system would be beneficial for the country as a whole. Enabling this kind of mutual beneficial networking is the prime objective of the “Knowledge and Partnership Bridges” (Gefyres Gnosis kai Synergasias) initiative. This new initiative aims to connect Greek professionals around the globe to form an e-community that can enhance the potential for national growth as well as provide opportunities for the individuals involved. We propose that a Diaspora Knowledge Network enabled by “Bridges” can enhance Greece’s bilateral and multilateral relations and bring together a global SΤ workforce to address challenges that extend beyond the capabilities of separate countries.